Antibacterial Properties of Tannic Acid and Related Compounds against the Fish PathogenCytophaga columnaris

Chitosan and tannic acid are known for their antibacterial properties. In the present in-situ study, their antibacterial and anti-adherent effects on biofilm formation on enamel were investigated. Six subjects carried upper jaw splints with bovine enamel specimens, allowing in-situ biofilm formation. During the two-day trial, subjects rinsed with experimental solutions that contained either chitosan, tannic acid (pH = 2.5), tannic acid (pH = 7) or hydrochloric acid. Water served as the negative and chlorhexidine as the positive control. Rinsing occurred four or five times following two different rinsing protocols to investigate both the immediate and long-lasting effects. After 48 h of intraoral exposure, the dental plaque was stained with LIVE/DEAD® BacLight, and fluorescence micrographs were evaluated by using the software ImageJ. The results were verified by scanning electron microscopy. Rinsing with chitosan resulted in little immediate antibacterial and anti-adherent effects but failed to show any long-lasting effect, while rinsing with tannic acid resulted in strong immediate and long-lasting effects. Except for a slightly lower antibacterial effect, the neutral solution of tannic acid was as good as the acidic solution. Hydrochloric acid showed neither an antibacterial nor an anti-adherent effect on dental biofilm formation. Experimental solutions containing tannic acid are promising anti-biofilm agents, irrespective of the pH values of the solutions. Chitosan, on the other hand, was not able to prevent biofilm formation.

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Tannic Acid with Antiviral and Antibacterial Activity as A Promising Component of Biomaterials—A Minireview

Materials ◽

10.3390/ma13143224 ◽

2020 ◽

Vol 13 (14) ◽

pp. 3224 ◽

Cited By ~ 2

Author(s):

Beata Kaczmarek

Keyword(s):

Physicochemical Properties ◽

Tannic Acid ◽

Phenolic Acid ◽

Antibacterial Properties ◽

Biological Properties ◽

In Vivo Studies ◽

Biomedical Sciences ◽

Simplex Virus

As a phenolic acid, tannic acid can be classified into a polyphenolic group. It has been widely studied in the biomedical field of science because it presents unique antiviral as well as antibacterial properties. Tannic acid has been reported to present the activity against Influeneza A virus, Papilloma viruses, noroviruses, Herpes simplex virus type 1 and 2, and human immunodeficiency virus (HIV) as well as activity against both Gram-positive and Gram-negative bacteria as Staphylococcus aureus, Escherichia coli, Streptococcus pyogenes, Enterococcus faecalis, Pseudomonas aeruginosa, Yersinia enterocolitica, Listeria innocua. Nowadays, compounds of natural origin constitute fundaments of material science, and the trend is called “from nature to nature”. Although biopolymers have found a broad range of applications in biomedical sciences, they do not present anti-microbial activity, and their physicochemical properties are rather poor. Biopolymers, however, may be modified with organic and inorganic additives which enhance their properties. Tannic acid, like phenolic acid, is classified into a polyphenolic group and can be isolated from natural sources, e.g., a pure compound or a component of a plant extract. Numerous studies have been carried out over the application of tannic acid as an additive to biopolymer materials due to its unique properties. On the one hand, it shows antimicrobial and antiviral activity, while on the other hand, it reveals promising biological properties, i.e., enhances the cell proliferation, tissue regeneration and wound healing processes. Tannic acid is added to different biopolymers, collagen and polysaccharides as chitosan, agarose and starch. Its activity has been proven by the determination of physicochemical properties, as well as the performance of in vitro and in vivo studies. This systematics review is a summary of current studies on tannic acid properties. It presents tannic acid as an excellent natural compound which can be used to eliminate pathogenic factors as well as a revision of current studies on tannic acid composed with biopolymers and active properties of the resulting complexes.

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Antibacterial properties and in vivo studies of tannic acid-stabilized silver–halloysite nanomaterials

Clay Minerals ◽

10.1180/clm.2020.17 ◽

2020 ◽

Vol 55 (2) ◽

pp. 112-119

Author(s):

Anna Stavitskaya ◽

Christina Shakhbazova ◽

Yulia Cherednichenko ◽

Läysän Nigamatzyanova ◽

Gölnur Fakhrullina ◽

...

Keyword(s):

Tannic Acid ◽

Antibacterial Properties ◽

Halloysite Nanotubes ◽

In Vivo Studies ◽

Negative Effects ◽

Antibacterial Performance ◽

Synthesis Strategy ◽

Clay Nanotubes

AbstractTannic acid-stabilized silver nanoparticles were synthesized in situ on halloysite clay nanotubes. The synthesis strategy included simple steps of tannic acid adsorption on clay nanotubes and further particle formation from silver salt solution. Pristine halloysite nanotubes as well as amino-modified clays were used for silver stabilization in water or ethanol. The materials were tested for antibacterial performance using three different methods. All of the materials produced showed antimicrobial activity. The pristine halloysite-based material with ~5 nm particles produced using ethanol as the solvent and tannic acid as the reducing agent showed the greatest antibacterial activity against Serratia marcescens. The materials were tested in vivo on Caenorhabditis elegans nematodes to ensure their safety, and they showed no negative effects on nematode growth and life expectancy.

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Investigation of antibacterial properties of novel papain immobilized on tannic acid modified Ag/CuFe2O4 magnetic nanoparticles

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2017.12.066 ◽

2018 ◽

Vol 109 ◽

pp. 720-731 ◽

Cited By ~ 25

Author(s):

Keziban Atacan ◽

Münteha Özacar ◽

Mahmut Özacar

Keyword(s):

Magnetic Nanoparticles ◽

Tannic Acid ◽

Antibacterial Properties

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Adhesive, Transparent Tannic Acid@ Sulfonated Lignin-PAM Ionic Conductive Hydrogel Electrode with Anti-UV, Antibacterial and Mild Antioxidant Function

Materials ◽

10.3390/ma12244135 ◽

2019 ◽

Vol 12 (24) ◽

pp. 4135 ◽

Cited By ~ 2

Author(s):

Qinhua Wang ◽

Hui Zhang ◽

Xiaofeng Pan ◽

Xiaojuan Ma ◽

Shilin Cao ◽

...

Keyword(s):

Tannic Acid ◽

Antibacterial Properties ◽

Physiological Signals ◽

Uv Resistance ◽

Conductive Hydrogel ◽

Antioxidant Function ◽

Electrocardiogram Ecg ◽

Ta Doping

Inspired by mussel adhesion chemistry and ion electronics, a novel Ca2+-tannic acid@ sulfonated lignin-polyacrylamide (TA@SL-PAM) hydrogel was prepared via Ca2+-TA@SL composites and the PAM system, where a Ca2+-TA@SL composite was fabricated via TA doping with SL and the subsequent adsorption of Ca2+. The properties of the hydrogel were thoroughly investigated and the hydrogel was presented as multifunctional. The introduction of Ca2+-TA@SL composites endowed the hydrogel with excellent conductivity, adhesion and ultraviolet (UV) resistance, and improved antioxidant and antibacterial properties. More importantly, the Ca2+-TA@SL-PAM hydrogel electrode could accurately detect physiological signals of human (e.g., electrocardiogram (ECG), electromyography (EMG).

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Gelation and the antioxidant and antibacterial properties of silk fibroin/tannic acid/Zn2+ mixtures

Polymer ◽

10.1016/j.polymer.2021.124090 ◽

2021 ◽

pp. 124090

Author(s):

Su Bin Bae ◽

Eunu Kim ◽

Kiramage Chathuranga ◽

Jong Soo Lee ◽

Won Ho Park

Keyword(s):

Silk Fibroin ◽

Tannic Acid ◽

Antibacterial Properties

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High-Performance Biocomposite Polyvinyl Alcohol (PVA) Films Modified with Cellulose Nanocrystals (CNCs), Tannic Acid (TA), and Chitosan (CS) for Food Packaging

Journal of Nanomaterials ◽

10.1155/2021/4821717 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

Ruowen Tan ◽

Feng Li ◽

You Zhang ◽

Zihui Yuan ◽

Xuefei Feng ◽

...

Keyword(s):

Polyvinyl Alcohol ◽

Tannic Acid ◽

Cellulose Nanocrystals ◽

High Performance ◽

Food Packaging ◽

Low Cost ◽

Antibacterial Properties ◽

Light Transmittance ◽

Thermal Stabilities ◽

Mechanical Performances

Polyvinyl alcohol (PVA) has been widely applied in industries for its low cost, nontoxicity, biodegradability, and renewable advantages. However, its unstable structure may not meet some strong physical and mechanical needs. In order to enhance the performances of the PVA film, cellulose nanocrystals (CNCs), tannic acid (TA), and chitosan (CS), working as a reinforcer, a crosslinker, and an antimicrobial agent, respectively, were introduced into the PVA matrix. The results indicated that CNCs, TA, and CS were evenly distributed and cohesively incorporated within the PVA matrix, which contributed to the good mechanical properties and thermal stabilities of biocomposite PVA films. Besides, the addition of TA remarkably improved the antiultraviolet and antioxidant capabilities of PVA films, although the light transmittance declined slightly. It was also observed that the pure PVA film and PVA reinforced with CNCs were incapable of protecting against bacteria, while the ones with CS had prominent antibacterial properties to Escherichia coli and Staphylococcus aureus. Overall, the resulting film presented a high potential utilization as a food packaging material for its outstanding physical and mechanical performances.

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